› 2iih

X-ray diffraction
1.75Å resolution

Crystal structure of the molybdenum cofactor biosynthesis protein C (TTHA1789) from thermus theromophilus HB8 (H32 form)

Released:
DOI: 10.2210/pdb2iih/pdb
PDB entry 2iih coloured by chain, front view.
PDB entry 2iih coloured by chain, side view.
PDB entry 2iih coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Jeyakanthan J, Kanaujia SP, Vasuki Ranjani C, Sekar K, Baba S, Chen L, Liu Z-J, Wang B-C, Ebihara A, Kuramitsu S, Shinkai A, Shiro Y, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177865 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclic pyranopterin monophosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 16.95 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SHE1 (Residues: 1-157; Coverage: 100%)
Gene names: TTHA1789, moaC
Sequence domains: MoaC family
Structure domains: Molybdopterin cofactor biosynthesis C (MoaC) domain

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: R32
Unit cell:
a: 106.573Å b: 106.573Å c: 59.251Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.196 0.217
Expression system: Escherichia coli BL21(DE3)

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