› 2im5

X-ray diffraction
2.2Å resolution

Crystal structure of Nicotinate phosphoribosyltransferase from Porphyromonas Gingivalis

Released:
DOI: 10.2210/pdb2im5/pdb
PDB entry 2im5 coloured by chain, front view.
PDB entry 2im5 coloured by chain, side view.
PDB entry 2im5 coloured by chain, top view.
Source organism: Porphyromonas gingivalis
Entry authors: Fedorov AA, Fedorov EV, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181786 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nicotinate phosphoribosyltransferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 394 amino acids
Theoretical weight: 45.53 KDa
Source organism: Porphyromonas gingivalis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7MXV0 (Residues: 1-394; Coverage: 100%)
Gene names: PG_0057, pncB
Sequence domains:
Structure domains: nicotinate phosphoribosyltransferase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 88.873Å b: 101.131Å c: 191.051Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.22 0.241
Expression system: Escherichia coli

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