› 2imm

X-ray diffraction
2Å resolution

Refined crystal structure of a recombinant immunoglobulin domain and a complementarity-determining region 1-grafted mutant

Released:
DOI: 10.2210/pdb2imm/pdb
PDB entry 2imm coloured by chain, front view.
PDB entry 2imm coloured by chain, side view.
PDB entry 2imm coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Refined crystal structure of a recombinant immunoglobulin domain and a complementarity-determining region 1-grafted mutant.
Steipe B, Plückthun A, Huber R
J Mol Biol 225 739-53 (1992)
PMID: 1602480

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213157 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
IGA-KAPPA MCPC603 FV (LIGHT CHAIN) Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 12.34 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6122
Unit cell:
a: 86.5Å b: 86.5Å c: 74.6Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.149 0.149 not available
Expression system: Not provided

Quick links

Citations

6 review citations

Anatomy of the antibody molecule.
Padlan EA. (1994)
5 more

5 mentions without citation

Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition.
Dondelinger et al. (2018)
4 more