› 2iqq

X-ray diffraction
2.66Å resolution

The Crystal Structure of Iron, Sulfur-Dependent L-serine dehydratase from Legionella pneumophila subsp. pneumophila

Released:
DOI: 10.2210/pdb2iqq/pdb
PDB entry 2iqq coloured by chain, front view.
PDB entry 2iqq coloured by chain, side view.
PDB entry 2iqq coloured by chain, top view.
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Entry authors: Kim Y, Hatzos C, Moy S, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Reaction catalysed: 
(1a) L-serine = 2-aminoprop-2-enoate + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178705 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L-serine dehydratase Chains: A, B
Molecule details ›
Chains: A, B
Length: 161 amino acids
Theoretical weight: 17.83 KDa
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5ZXE1 (Residues: 4-161; Coverage: 35%)
Gene names: lpg0790, sda-2
Sequence domains: Serine dehydratase beta chain
Structure domains: D-3-phosphoglycerate dehydrogenase; domain 3

Ligands and Environments

1 bound ligand:
Ligand MG 2 x MG
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 120.705Å b: 77.151Å c: 56.158Å
α: 90° β: 117.91° γ: 90°
R-values:
R R work R free
0.18 0.174 0.226
Expression system: Escherichia coli

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