› 2iuj

X-ray diffraction
2.4Å resolution

Crystal Structure of Soybean Lipoxygenase-B

Released:
DOI: 10.2210/pdb2iuj/pdb
PDB entry 2iuj coloured by chain, front view.
PDB entry 2iuj coloured by chain, side view.
PDB entry 2iuj coloured by chain, top view.
Source organism: Glycine max
Primary publication:
Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3.
Youn B, Sellhorn GE, Mirchel RJ, Gaffney BJ, Grimes HD, Kang C
Proteins 65 1008-20 (2006)
PMID: 17022084

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174993 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lipoxygenase Chain: A
Molecule details ›
Chain: A
Length: 853 amino acids
Theoretical weight: 96.78 KDa
Source organism: Glycine max
Expression system: Escherichia coli
UniProt:
  • Canonical: Q43446 (Residues: 1-853; Coverage: 100%)
Gene name: vlxB
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FE 1 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P212121
Unit cell:
a: 99.99Å b: 105.31Å c: 105.92Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.05 0.05 not available
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling.
Horn et al. (2015)
3 more

8 mentions without citation

The structural basis for specificity in lipoxygenase catalysis.
Newcomer et al. (2015)
7 more