› 2ius

X-ray diffraction
2.7Å resolution

E. coli FtsK motor domain

Released:
DOI: 10.2210/pdb2ius/pdb
PDB entry 2ius coloured by chain, front view.
PDB entry 2ius coloured by chain, side view.
PDB entry 2ius coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Double-stranded DNA translocation: structure and mechanism of hexameric FtsK.
Massey TH, Mercogliano CP, Yates J, Sherratt DJ, Löwe J
Mol Cell 23 457-69 (2006)
PMID: 16916635

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155533 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA translocase FtsK Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 512 amino acids
Theoretical weight: 56.27 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P46889 (Residues: 818-1329; Coverage: 39%)
Gene names: JW0873, b0890, ftsK
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 97.6Å b: 117.2Å c: 132.8Å
α: 90° β: 100.5° γ: 90°
R-values:
R R work R free
0.246 0.246 0.298
Expression system: Escherichia coli

Quick links

Citations

47 review citations

Structure and mechanism of helicases and nucleic acid translocases.
Singleton et al. (2007)
46 more

6 mentions without citation

HCIV-1 and Other Tailless Icosahedral Internal Membrane-Containing Viruses of the Family Sphaerolipoviridae.
Demina et al. (2017)
5 more