› 2iuu

X-ray diffraction
2.9Å resolution

P. aeruginosa FtsK motor domain, hexamer

Released:
DOI: 10.2210/pdb2iuu/pdb
PDB entry 2iuu coloured by chain, front view.
PDB entry 2iuu coloured by chain, side view.
PDB entry 2iuu coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Double-stranded DNA translocation: structure and mechanism of hexameric FtsK.
Massey TH, Mercogliano CP, Yates J, Sherratt DJ, Löwe J
Mol Cell 23 457-69 (2006)
PMID: 16916635

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191242 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA translocase FtsK Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 491 amino acids
Theoretical weight: 54 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9I0M3 (Residues: 247-728; Coverage: 59%)
Gene names: PA2615, ftsK
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ADP 6 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21212
Unit cell:
a: 140.012Å b: 221.757Å c: 134.075Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 0.259
Expression system: Escherichia coli

Quick links

Citations

39 review citations

Structure and mechanism of helicases and nucleic acid translocases.
Singleton et al. (2007)
38 more

27 mentions without citation

Loading strategies of ring-shaped nucleic acid translocases and helicases.
O'Shea et al. (2014)
26 more