› 2ivm

X-ray diffraction
2.5Å resolution

Crystal structure of a transcriptional regulator

Released:
DOI: 10.2210/pdb2ivm/pdb
PDB entry 2ivm coloured by chain, front view.
PDB entry 2ivm coloured by chain, side view.
PDB entry 2ivm coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Mechanistic insights from the crystal structures of a feast/famine regulatory protein from Mycobacterium tuberculosis H37Rv.
Shrivastava T, Ramachandran R
Nucleic Acids Res 35 7324-35 (2007)
PMID: 17962306

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161261 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH asnC-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 150 amino acids
Theoretical weight: 16.52 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P96896 (Residues: 1-150; Coverage: 100%)
Gene names: MT3390, lrp
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P42212
Unit cell:
a: 100.827Å b: 100.827Å c: 99.503Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.255
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Role of the Extremolytes Ectoine and Hydroxyectoine as Stress Protectants and Nutrients: Genetics, Phylogenomics, Biochemistry, and Structural Analysis.
Czech et al. (2018)
3 more

4 mentions without citation

Mechanistic insights from the crystal structures of a feast/famine regulatory protein from Mycobacterium tuberculosis H37Rv.
Shrivastava et al. (2007)
3 more