› 2j16

X-ray diffraction
2.7Å resolution

Function and Biology Details

Reaction catalysed: 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154121 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Dual-specificity protein phosphatase SDP1 Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 20.9 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P40479 (Residues: 17-198; Coverage: 87%)
Gene names: SDP1, YIL113W
Sequence domains: Dual specificity phosphatase, catalytic domain
Structure domains: Protein tyrosine phosphatase superfamily
Dual-specificity protein phosphatase SDP1 Chain: B
Molecule details ›
Chain: B
Length: 182 amino acids
Theoretical weight: 20.87 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P40479 (Residues: 17-198; Coverage: 87%)
Gene names: SDP1, YIL113W
Sequence domains: Dual specificity phosphatase, catalytic domain
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand SO4 3 x SO4
1 modified residue:
Ligand CSD 1 x CSD

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P41212
Unit cell:
a: 77.342Å b: 77.342Å c: 152.885Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.23 0.257
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Redox-based regulation of signal transduction: principles, pitfalls, and promises.
Janssen-Heininger et al. (2008)
10 more