› 2j3d

X-ray diffraction
2.6Å resolution

Native monoclinic form of Torpedo acetylcholinesterase

Released:
DOI: 10.2210/pdb2j3d/pdb
PDB entry 2j3d coloured by chain, front view.
PDB entry 2j3d coloured by chain, side view.
PDB entry 2j3d coloured by chain, top view.
Source organism: Tetronarce californica
Entry authors: Harel M, Sussman JL

Function and Biology Details

Reaction catalysed: 
Acetylcholine + H(2)O = choline + acetate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholinesterase Chain: A
Molecule details ›
Chain: A
Length: 543 amino acids
Theoretical weight: 61.33 KDa
Source organism: Tetronarce californica
Expression system: Not provided
UniProt:
  • Canonical: P04058 (Residues: 22-564; Coverage: 96%)
Gene name: ache
Sequence domains: Carboxylesterase family
Structure domains: alpha/beta hydrolase

Ligands and Environments

2 bound ligands:
Ligand NAG 3 x NAG
Ligand MG 5 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 128.74Å b: 105.49Å c: 70.6Å
α: 90° β: 106.62° γ: 90°
R-values:
R R work R free
0.217 0.217 0.261
Expression system: Not provided

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