› 2j4t

X-ray diffraction
2.02Å resolution

Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein

Released:
DOI: 10.2210/pdb2j4t/pdb
PDB entry 2j4t coloured by chain, front view.
PDB entry 2j4t coloured by chain, side view.
PDB entry 2j4t coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Biological and structural features of murine angiogenin-4, an angiogenic protein.
Crabtree B, Holloway DE, Baker MD, Acharya KR, Subramanian V
Biochemistry 46 2431-43 (2007)
PMID: 17279775

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174817 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin-4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 144 amino acids
Theoretical weight: 16.58 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3TMQ6 (Residues: 1-144; Coverage: 100%)
Gene name: Ang4
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: C2
Unit cell:
a: 97.472Å b: 31.422Å c: 95.471Å
α: 90° β: 118.85° γ: 90°
R-values:
R R work R free
0.229 0.229 0.294
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis.
Bevins et al. (2011)
4 more

3 mentions without citation

Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications.
Kazakou et al. (2008)
2 more