› 2j58

X-ray diffraction
2.25Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194907 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative outer membrane lipoprotein Wza Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 359 amino acids
Theoretical weight: 40.1 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X4B7 (Residues: 22-379; Coverage: 95%)
Gene name: wza
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand OCT 8 x OCT
Ligand HEX 8 x HEX
Ligand SO4 16 x SO4
1 modified residue:
Ligand MSE 80 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 94.719Å b: 215.268Å c: 220.892Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.226
Expression system: Escherichia coli

Quick links

Citations

49 review citations

Outer membrane permeability and antibiotic resistance.
Delcour AH. (2009)
48 more

17 mentions without citation

E. coli Group 1 Capsular Polysaccharide Exportation Nanomachinary as a Plausible Antivirulence Target in the Perspective of Emerging Antimicrobial Resistance.
Sachdeva et al. (2017)
16 more