2jab

X-ray diffraction
1.7Å resolution

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162771 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
H10-2-G3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 136 amino acids
Theoretical weight: 14.62 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: C2
Unit cell:
a: 152.08Å b: 52.191Å c: 70.164Å
α: 90° β: 105.19° γ: 90°
R-values:
R R work R free
0.18 0.178 0.212
Expression system: Escherichia coli