› 2jeu

X-ray diffraction
2.8Å resolution

Transcription activator structure reveals redox control of a replication initiation reaction

Released:
DOI: 10.2210/pdb2jeu/pdb
PDB entry 2jeu coloured by chain, front view.
PDB entry 2jeu coloured by chain, side view.
PDB entry 2jeu coloured by chain, top view.
Source organism: Deltapapillomavirus 4
Primary publication:
Transcription activator structure reveals redox control of a replication initiation reaction.
Sanders CM, Sizov D, Seavers PR, Ortiz-Lombardía M, Antson AA
Nucleic Acids Res 35 3504-15 (2007)
PMID: 17478495

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136581 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein E2 Chain: A
Molecule details ›
Chain: A
Length: 209 amino acids
Theoretical weight: 23.91 KDa
Source organism: Deltapapillomavirus 4
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03122 (Residues: 1-209; Coverage: 51%)
Gene name: E2
Sequence domains: E2 (early) protein, N terminal
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P6122
Unit cell:
a: 61.539Å b: 61.539Å c: 236.317Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.233 0.281
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Replication and partitioning of papillomavirus genomes.
McBride AA. (2008)
2 more

5 mentions without citation

The papillomavirus E2 proteins.
McBride AA. (2013)
4 more