› 2ji4

X-ray diffraction
2.55Å resolution

Human phosphoribosylpyrophosphate synthetase - associated protein 41 (PAP41)

Released:
DOI: 10.2210/pdb2ji4/pdb
PDB entry 2ji4 coloured by chain, front view.
PDB entry 2ji4 coloured by chain, side view.
PDB entry 2ji4 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Moche M, Lehtio L, Arrowsmith C, Berglund H, Busam R, Collins R, Dahlgren LG, Edwards A, Flodin S, Flores A, Graslund S, Hammarstrom M, Hallberg BM, Holmberg-Schiavone L, Johansson I, Karlberg T, Kotenyova T, Nyman T, Ogg D, Persson C, Sagemark J, Stenmark P, Sundstrom M, Thorsell AG, Van Den Berg S, Weigelt J, Nordlund P

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129923 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoribosyl pyrophosphate synthase-associated protein 2 Chain: A
Molecule details ›
Chain: A
Length: 379 amino acids
Theoretical weight: 42.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60256 (Residues: 12-369; Coverage: 97%)
Gene name: PRPSAP2
Sequence domains:
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: R32
Unit cell:
a: 104.4Å b: 104.4Å c: 192Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.206 0.273
Expression system: Escherichia coli BL21(DE3)

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