› 2jn3

Solution NMR

NMR structure of cl-BABP complexed to chenodeoxycholic acid

Released:
DOI: 10.2210/pdb2jn3/pdb
PDB entry 2jn3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2jn3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2jn3 coloured by chain, ensemble of 20 models, top view.
Source organism: Gallus gallus
Primary publication:
Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR.
Eliseo T, Ragona L, Catalano M, Assfalg M, Paci M, Zetta L, Molinari H, Cicero DO
Biochemistry 46 12557-67 (2007)
PMID: 17929837

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160367 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, liver Chain: A
Molecule details ›
Chain: A
Length: 125 amino acids
Theoretical weight: 14.1 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P80226 (Residues: 2-126; Coverage: 99%)
Gene name: FABP1
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand JN3 2 x JN3
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Review: the liver bile acid-binding proteins.
Monaco HL. (2009)
1 more

3 mentions without citation

Bile acid binding protein: a versatile host of small hydrophobic ligands for applications in the fields of MRI contrast agents and bio-nanomaterials.
Pagano et al. (2013)
2 more