Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139874 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA excision repair protein ERCC-1
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 15.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
Structure domains: Rossmann fold
Length: 133 amino acids
Theoretical weight: 15.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P07992 (Residues: 96-214; Coverage: 40%)
Sequence domains: Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
Structure domains: Rossmann fold
DNA repair protein complementing XP-A cells
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.52 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 14 amino acids
Theoretical weight: 1.52 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P23025 (Residues: 67-80; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
simulated annealing
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
