› 2jrg

Solution NMR

NMR solution structure of the anticodon of E. coli TRNA-VAL3 with 2 modifications (cmo5U34 M6A37)

Released:
DOI: 10.2210/pdb2jrg/pdb
PDB entry 2jrg coloured by chain, ensemble of 11 models, front view.
PDB entry 2jrg coloured by chain, ensemble of 11 models, side view.
PDB entry 2jrg coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding.
Vendeix FA, Dziergowska A, Gustilo EM, Graham WD, Sproat B, Malkiewicz A, Agris PF
Biochemistry 47 6117-29 (2008)
PMID: 18473483

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196393 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
5'-R(*CP*CP*UP*CP*CP*CP*UP*(CM0)P*AP*CP*(6MZ)P*AP*GP*GP*AP*GP*G)-3' Chain: A
Molecule details ›
Chain: A
Length: 17 nucleotides
Theoretical weight: 5.49 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 6MZ 1 x 6MZ

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

4 review citations

Celebrating wobble decoding: Half a century and still much is new.
Agris et al. (2018)
3 more

1 mention without citation

The Importance of Being Modified: The Role of RNA Modifications in Translational Fidelity.
Agris et al. (2017)