› 2jv6

Solution NMR

YF ED3 Protein NMR Structure

Released:
DOI: 10.2210/pdb2jv6/pdb
PDB entry 2jv6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2jv6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2jv6 coloured by chain, ensemble of 20 models, top view.
Source organism: Yellow fever virus
Entry authors: Volk DE, Gandham SHA, May FJ, Anderson A, Barrett ADT, Gorenstein DG

Function and Biology Details

Reactions catalysed: 
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179559 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope protein E Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 11.95 KDa
Source organism: Yellow fever virus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6DV88 (Residues: 572-683; Coverage: 3%)
Sequence domains: Flavivirus glycoprotein, immunoglobulin-like domain
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics, DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

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