› 2jw8

Solution NMR

Solution structure of stereo-array isotope labelled (SAIL) C-terminal dimerization domain of SARS coronavirus nucleocapsid protein

Released:
DOI: 10.2210/pdb2jw8/pdb
PDB entry 2jw8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2jw8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2jw8 coloured by chain, ensemble of 20 models, top view.
Source organism: Severe acute respiratory syndrome-related coronavirus
Primary publication:
Solution structure of the c-terminal dimerization domain of SARS coronavirus nucleocapsid protein solved by the SAIL-NMR method.
Takeda M, Chang CK, Ikeya T, Güntert P, Chang YH, Hsu YL, Huang TH, Kainosho M
J Mol Biol 380 608-22 (2008)
PMID: 18561946

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157823 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 128 amino acids
Theoretical weight: 14.56 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Cell-free synthesis
UniProt:
  • Canonical: P59595 (Residues: 248-365; Coverage: 28%)
Gene names: 9a, N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, TORSION ANGLE DYNAMICS
Expression system: Cell-free synthesis

Quick links

Citations

21 review citations

The coronavirus nucleocapsid is a multifunctional protein.
McBride et al. (2014)
20 more

14 mentions without citation

From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses.
Hilgenfeld et al. (2013)
13 more