› 2jx1

Solution NMR

Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA

Released:
DOI: 10.2210/pdb2jx1/pdb
PDB entry 2jx1 coloured by chain, ensemble of 10 models, front view.
PDB entry 2jx1 coloured by chain, ensemble of 10 models, side view.
PDB entry 2jx1 coloured by chain, ensemble of 10 models, top view.
Source organism: Mus musculus
Entry authors: Gamsjaeger R, Swanton MK, Kobus FJ, Lehtomaki E, Lowry JA, Kwan AH, Matthews JM, Mackay JP

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115439 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Myelin transcription factor 1 Chain: A
Molecule details ›
Chain: A
Length: 31 amino acids
Theoretical weight: 3.16 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8CFC2 (Residues: 843-873; Coverage: 3%)
Gene names: Kiaa0835, Myt1, Nzf2
Sequence domains: Zinc finger, C2HC type
DNA (5'-D(*DAP*DCP*DCP*DGP*DAP*DAP*DAP*DGP*DTP*DTP*DCP*DAP*DC)-3') Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 3.94 KDa
Source organism: Mus musculus
Expression system: Not provided
DNA (5'-D(*DGP*DTP*DGP*DAP*DAP*DCP*DTP*DTP*DTP*DCP*DGP*DGP*DT)-3') Chain: C
Molecule details ›
Chain: C
Length: 13 nucleotides
Theoretical weight: 4 KDa
Source organism: Mus musculus
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: HADDOCK docking, simulated annealing
Expression systems:
  • Escherichia coli BL21
  • Not provided

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