› 2jxv

Solution NMR

Solution structure of a let-7 miRNA:lin-41 mRNA complex from C. elegans

Released:
DOI: 10.2210/pdb2jxv/pdb
PDB entry 2jxv coloured by chain, ensemble of 10 models, front view.
PDB entry 2jxv coloured by chain, ensemble of 10 models, side view.
PDB entry 2jxv coloured by chain, ensemble of 10 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a let-7 miRNA:lin-41 mRNA complex from C. elegans.
Cevec M, Thibaudeau C, Plavec J
Nucleic Acids Res 36 2330-7 (2008)
PMID: 18296482

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196402 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (33-MER) Chain: A
Molecule details ›
Chain: A
Length: 33 nucleotides
Theoretical weight: 10.63 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, energy minimization
Expression system: Not provided

Quick links

Citations

1 review citation

Effective tools for RNA-derived therapeutics: siRNA interference or miRNA mimicry.
Wang et al. (2021)
10 other articles

6 mentions without citation

Mechanism of microRNA-target interaction: molecular dynamics simulations and thermodynamics analysis.
Wang et al. (2010)
5 more