› 2jy5

Solution NMR

NMR structure of Ubiquilin 1 UBA domain

Released:
DOI: 10.2210/pdb2jy5/pdb
PDB entry 2jy5 coloured by chain, ensemble of 10 models, front view.
PDB entry 2jy5 coloured by chain, ensemble of 10 models, side view.
PDB entry 2jy5 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains.
Zhang D, Raasi S, Fushman D
J Mol Biol 377 162-80 (2008)
PMID: 18241885

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193973 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquilin-1 Chain: A
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 5.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UMX0 (Residues: 541-586; Coverage: 8%)
Gene names: DA41, PLIC1, UBQLN1
Sequence domains: UBA/TS-N domain
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

23 review citations

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series.
Ikeda et al. (2008)
22 more

10 mentions without citation

Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains.
Zhang et al. (2008)
9 more