› 2jyd

Solution NMR

Structure of the fifth zinc finger of Myelin Transcription Factor 1

Released:
DOI: 10.2210/pdb2jyd/pdb
PDB entry 2jyd coloured by chain, ensemble of 20 models, front view.
PDB entry 2jyd coloured by chain, ensemble of 20 models, side view.
PDB entry 2jyd coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Structural and biophysical analysis of the DNA binding properties of myelin transcription factor 1.
Gamsjaeger R, Swanton MK, Kobus FJ, Lehtomaki E, Lowry JA, Kwan AH, Matthews JM, Mackay JP
J Biol Chem 283 5158-67 (2008)
PMID: 18073212

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183954 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myelin transcription factor 1 Chain: A
Molecule details ›
Chain: A
Length: 46 amino acids
Theoretical weight: 4.65 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8CFC2 (Residues: 837-880; Coverage: 4%)
Gene names: Kiaa0835, Myt1, Nzf2
Sequence domains: Zinc finger, C2HC type

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Protein design: toward functional metalloenzymes.
Yu et al. (2014)
3 more

3 mentions without citation

A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers.
Gamsjaeger et al. (2013)
2 more