Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Talin-1 and Layilin (preferred)
PDBe Complex ID:
PDB-CPX-157125 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Talin-1
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.53 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21
UniProt:
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Length: 92 amino acids
Theoretical weight: 10.53 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P54939 (Residues: 309-400; Coverage: 4%)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Layilin
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.82 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 15 amino acids
Theoretical weight: 1.82 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: Q8C351 (Residues: 367-381; Coverage: 4%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
simulated annealing, molecular dynamics
Expression systems:
- Escherichia coli BL21
- Not provided
