› 2k0n

Solution NMR

Solution Structure of Yeast Gal11p kix domain

Released:
DOI: 10.2210/pdb2k0n/pdb
PDB entry 2k0n coloured by chain, ensemble of 20 models, front view.
PDB entry 2k0n coloured by chain, ensemble of 20 models, side view.
PDB entry 2k0n coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Thakur JK, Arthanari H, Yang F, Pan SJ, Fan X, Breger J, Frueh DP, Gulshan K, Li DK, Mylonakis E, Struhl K, Moye-Rowley WS, Cormack BP, Wagner G, Näär AM
Nature 452 604-9 (2008)
PMID: 18385733

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148682 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mediator of RNA polymerase II transcription subunit 15 Chain: A
Molecule details ›
Chain: A
Length: 85 amino acids
Theoretical weight: 9.41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P19659 (Residues: 6-90; Coverage: 8%)
Gene names: ABE1, GAL11, MED15, RAR3, SDS4, SPT13, YOL051W
Sequence domains: KIX domain
Structure domains: Coactivator CBP, KIX domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

42 review citations

Efflux-mediated antifungal drug resistance.
Cannon et al. (2009)
41 more

6 mentions without citation

Twenty years of Mediator complex structural studies.
Verger et al. (2019)
5 more