› 2k17

Solution NMR

Solution structure of the TAF3 PHD domain in complex with a H3K4me3 peptide

Released:
DOI: 10.2210/pdb2k17/pdb
PDB entry 2k17 coloured by chain, ensemble of 20 models, front view.
PDB entry 2k17 coloured by chain, ensemble of 20 models, side view.
PDB entry 2k17 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Entry authors: van Ingen H, van Schaik FMA, Wienk H, Timmers M, Boelens R

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162802 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
H3K4me3 peptide Chain: P
Molecule details ›
Chain: P
Length: 13 amino acids
Theoretical weight: 1.41 KDa
Source organism: Mus musculus
Expression system: Not provided
Transcription initiation factor TFIID subunit 3 Chain: A
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.61 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q5HZG4 (Residues: 857-924; Coverage: 7%)
Gene name: Taf3
Sequence domains: PHD-finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
1 modified residue:
Ligand M3L 1 x M3L

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: simulated annealing
Expression systems:
  • Not provided
  • Escherichia coli BL21

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