› 2k1i

Solution NMR

Synthesis, Structure and Activities of an Oral Mucosal Alpha-Defensin from Rhesus Macaque

Released:
DOI: 10.2210/pdb2k1i/pdb
PDB entry 2k1i coloured by chain, ensemble of 10 models, front view.
PDB entry 2k1i coloured by chain, ensemble of 10 models, side view.
PDB entry 2k1i coloured by chain, ensemble of 10 models, top view.
Source organism: Macaca mulatta
Primary publication:
Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque.
Vasudevan S, Yuan J, Osapay G, Tran P, Tai K, Liang W, Kumar V, Selsted ME, Cocco MJ
J Biol Chem 283 35869-77 (2008)
PMID: 18930922

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110168 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mammalian defensins domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 32 amino acids
Theoretical weight: 3.75 KDa
Source organism: Macaca mulatta
Expression system: Not provided
UniProt:
  • Canonical: B5AKV3 (Residues: 62-93; Coverage: 43%)
Gene name: ROAD-1
Sequence domains: Mammalian defensin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

5 citation in other articles

Comparative genomics and evolution of the alpha-defensin multigene family in primates.
Das et al. (2010)
4 more

2 mentions without citation

Arginine in α-defensins: differential effects on bactericidal activity correspond to geometry of membrane curvature generation and peptide-lipid phase behavior.
Schmidt et al. (2012)
1 more