› 2k2a

Solution NMR

Solution Structure of the Apo C terminal domain of Lethocerus troponin C isoform F1

Released:
DOI: 10.2210/pdb2k2a/pdb
PDB entry 2k2a coloured by chain, ensemble of 10 models, front view.
PDB entry 2k2a coloured by chain, ensemble of 10 models, side view.
PDB entry 2k2a coloured by chain, ensemble of 10 models, top view.
Source organism: Lethocerus indicus
Primary publication:
Solution structure of the Apo C-terminal domain of the Lethocerus F1 troponin C isoform.
De Nicola GF, Martin S, Bullard B, Pastore A
Biochemistry 49 1719-26 (2010)
PMID: 20104876

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183105 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EF-hand domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 7.85 KDa
Source organism: Lethocerus indicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q868D4 (Residues: 89-158; Coverage: 44%)
Gene name: tnC4
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

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Citations

2 review citations

Regulating the contraction of insect flight muscle.
Bullard et al. (2011)
1 more

2 mentions without citation

First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.
Li et al. (2012)
1 more