› 2k36

Solution NMR

Structure ensemble Backbone and side-chain 1H, 13C, and 15N Chemical Shift Assignments, 1H-15N RDCs and 1H-1H nOe restraints for protein K7 from the Vaccinia virus

Released:
DOI: 10.2210/pdb2k36/pdb
PDB entry 2k36 coloured by chain, ensemble of 15 models, front view.
PDB entry 2k36 coloured by chain, ensemble of 15 models, side view.
PDB entry 2k36 coloured by chain, ensemble of 15 models, top view.
Source organism: Vaccinia virus
Primary publication:
Poxvirus K7 protein adopts a Bcl-2 fold: biochemical mapping of its interactions with human DEAD box RNA helicase DDX3.
Kalverda AP, Thompson GS, Vogel A, Schröder M, Bowie AG, Khan AR, Homans SW
J Mol Biol 385 843-53 (2009)
PMID: 18845156

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159478 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein K7 Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 17.49 KDa
Source organism: Vaccinia virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P68466 (Residues: 1-149; Coverage: 100%)
Gene names: K7R, OPG044, VACWR039
Sequence domains: Poxvirus Bcl-2-like proteins
Structure domains: dsDNA poxvirus

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing, simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

25 review citations

Multiple functions of BCL-2 family proteins.
Hardwick et al. (2013)
24 more

3 mentions without citation

Poxvirus proteomics and virus-host protein interactions.
Van Vliet et al. (2009)
2 more