› 2k4w

Solution NMR

The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica

Released:
DOI: 10.2210/pdb2k4w/pdb
PDB entry 2k4w coloured by chain, ensemble of 30 models, front view.
PDB entry 2k4w coloured by chain, ensemble of 30 models, side view.
PDB entry 2k4w coloured by chain, ensemble of 30 models, top view.
Source organism: Salmonella enterica subsp. enterica serovar Choleraesuis
Primary publication:
The solution structure of the monomeric copper, zinc superoxide dismutase from Salmonella enterica: structural insights to understand the evolution toward the dimeric structure.
Mori M, Jiménez B, Piccioli M, Battistoni A, Sette M
Biochemistry 47 12954-63 (2008)
PMID: 19006322

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180635 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 15.74 KDa
Source organism: Salmonella enterica subsp. enterica serovar Choleraesuis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q704S6 (Residues: 20-173; Coverage: 100%)
Gene names: GB124_19275, GB355_00400, GB421_17745, GB623_01585, GBV40_17665, GBV66_03230, GBV92_17355, GBX10_06805, GBY24_18375, GBY28_17765, GBZ03_17175, GND64_000319, sodC, sodC2
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

2 bound ligands:
Ligand CU1 1 x CU1
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 97%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Immunoglobulin domains in Escherichia coli and other enterobacteria: from pathogenesis to applications in antibody technologies.
Bodelón et al. (2013)
7 other articles

2 mentions without citation

Structural, Functional, and Immunogenic Insights on Cu,Zn Superoxide Dismutase Pathogenic Virulence Factors from Neisseria meningitidis and Brucella abortus.
Pratt et al. (2015)
1 more