› 2k6b

Solution NMR

Solution structure of 1-112 fragment of human programmed cell death 5 protein

Released:
DOI: 10.2210/pdb2k6b/pdb
PDB entry 2k6b coloured by chain, ensemble of 20 models, front view.
PDB entry 2k6b coloured by chain, ensemble of 20 models, side view.
PDB entry 2k6b coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure-function correlation of human programmed cell death 5 protein.
Yao H, Xu L, Feng Y, Liu D, Chen Y, Wang J
Arch Biochem Biophys 486 141-9 (2009)
PMID: 19358820

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127072 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Programmed cell death protein 5 Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14737 (Residues: 2-112; Coverage: 89%)
Gene names: PDCD5, TFAR19
Sequence domains: Double-stranded DNA-binding domain
Structure domains: PDCD5-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Serum programmed cell death protein 5 (PDCD5) levels is upregulated in liver diseases.
Chen et al. (2013)
2 more

4 mentions without citation

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding.
Tracy et al. (2014)
3 more