› 2k6m

Solution NMR

Solution Structure of Human Supervillin Headpiece

Released:
DOI: 10.2210/pdb2k6m/pdb
PDB entry 2k6m coloured by chain, ensemble of 22 models, front view.
PDB entry 2k6m coloured by chain, ensemble of 22 models, side view.
PDB entry 2k6m coloured by chain, ensemble of 22 models, top view.
Source organism: Homo sapiens
Primary publication:
How to arm a supervillin: designing F-actin binding activity into supervillin headpiece.
Brown JW, Vardar-Ulu D, McKnight CJ
J Mol Biol 393 608-18 (2009)
PMID: 19683541

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131929 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Supervillin Chain: S
Molecule details ›
Chain: S
Length: 67 amino acids
Theoretical weight: 7.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95425 (Residues: 2149-2214; Coverage: 3%)
Gene name: SVIL
Sequence domains: Villin headpiece domain
Structure domains: Villin headpiece domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

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Citations

1 review citation

Refined views of multi-protein complexes in the erythrocyte membrane.
Mankelow et al. (2012)
10 other articles

2 mentions without citation

How to arm a supervillin: designing F-actin binding activity into supervillin headpiece.
Brown et al. (2009)
1 more