› 2k8y

Solution NMR

Solution NMR Structure of Cgi121 from Methanococcus jannaschii. Northeast Structural Genomics Consortium Target MJ0187

Released:
DOI: 10.2210/pdb2k8y/pdb
PDB entry 2k8y coloured by chain, ensemble of 10 models, front view.
PDB entry 2k8y coloured by chain, ensemble of 10 models, side view.
PDB entry 2k8y coloured by chain, ensemble of 10 models, top view.
Source organism: Methanocaldococcus jannaschii
Primary publication:
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mao DY, Neculai D, Downey M, Orlicky S, Haffani YZ, Ceccarelli DF, Ho JS, Szilard RK, Zhang W, Ho CS, Wan L, Fares C, Rumpel S, Kurinov I, Arrowsmith CH, Durocher D, Sicheri F
Mol Cell 32 259-75 (2008)
PMID: 18951093

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176447 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein Cgi121 Chain: A
Molecule details ›
Chain: A
Length: 150 amino acids
Theoretical weight: 17.09 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q57646 (Residues: 1-145; Coverage: 100%)
Gene names: MJ0187, cgi121
Sequence domains: Kinase binding protein CGI-121
Structure domains: CGI121/TPRKB

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Protein Ser/Thr/Tyr phosphorylation in the Archaea.
Kennelly PJ. (2014)
4 more

2 mentions without citation

The structural and functional workings of KEOPS.
Beenstock et al. (2021)
1 more