› 2kbb

Solution NMR

Solution Structure of the R9 Domain of Talin

Released:
DOI: 10.2210/pdb2kbb/pdb
PDB entry 2kbb coloured by chain, ensemble of 20 models, front view.
PDB entry 2kbb coloured by chain, ensemble of 20 models, side view.
PDB entry 2kbb coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
The structure of an interdomain complex that regulates talin activity.
Goult BT, Bate N, Anthis NJ, Wegener KL, Gingras AR, Patel B, Barsukov IL, Campbell ID, Roberts GC, Critchley DR
J Biol Chem 284 15097-106 (2009)
PMID: 19297334

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Talin-1 Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 18.25 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P26039 (Residues: 1655-1822; Coverage: 7%)
Gene names: Tln, Tln1
Structure domains: Talin, central domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: SIMULATED ANNEALING, MOLECULAR DYNAMICS, TORSION ANGLE DYNAMICS
Expression system: Escherichia coli

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Citations

23 review citations

Talins and kindlins: partners in integrin-mediated adhesion.
Calderwood et al. (2013)
22 more

6 mentions without citation

The structure of an interdomain complex that regulates talin activity.
Goult et al. (2009)
5 more