› 2kbx

Solution NMR

Solution structure of ILK-PINCH complex

Released:
DOI: 10.2210/pdb2kbx/pdb
PDB entry 2kbx coloured by chain, ensemble of 20 models, front view.
PDB entry 2kbx coloured by chain, ensemble of 20 models, side view.
PDB entry 2kbx coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry author: Qin J

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155700 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin-linked protein kinase Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13418 (Residues: 1-171; Coverage: 38%)
Gene names: ILK, ILK1, ILK2
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Ankyrin repeat-containing domain
LIM and senescent cell antigen-like-containing domain protein 1 Chain: B
Molecule details ›
Chain: B
Length: 70 amino acids
Theoretical weight: 7.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P48059 (Residues: 1-70; Coverage: 22%)
Gene names: LIMS1, PINCH, PINCH1
Sequence domains: LIM domain
Structure domains: Cysteine Rich Protein

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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