› 2kc2

Solution NMR

NMR structure of the F1 domain (residues 86-202) of the talin

Released:
DOI: 10.2210/pdb2kc2/pdb
PDB entry 2kc2 coloured by chain, ensemble of 10 models, front view.
PDB entry 2kc2 coloured by chain, ensemble of 10 models, side view.
PDB entry 2kc2 coloured by chain, ensemble of 10 models, top view.
Source organism: Mus musculus
Primary publication:
Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL
EMBO J 29 1069-80 (2010)
PMID: 20150896

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Talin-1 Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 15.03 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P26039 (Residues: 86-202; Coverage: 5%)
Gene names: Tln, Tln1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

33 review citations

Talins and kindlins: partners in integrin-mediated adhesion.
Calderwood et al. (2013)
32 more

4 mentions without citation

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Goult et al. (2010)
3 more