› 2kda

Solution NMR

Solution Structure of DNA Containing Alpha-OH-PdG: the Mutagenic Adduct Produced by Acrolein

Released:
DOI: 10.2210/pdb2kda/pdb
PDB entry 2kda coloured by chain, ensemble of 26 models, front view.
PDB entry 2kda coloured by chain, ensemble of 26 models, side view.
PDB entry 2kda coloured by chain, ensemble of 26 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of DNA containing alpha-OH-PdG: the mutagenic adduct produced by acrolein.
Zaliznyak T, Bonala R, Attaluri S, Johnson F, de los Santos C
Nucleic Acids Res 37 2153-63 (2009)
PMID: 19223332

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115467 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*CP*GP*TP*AP*CP*(63H)P*CP*AP*TP*GP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 11 nucleotides
Theoretical weight: 3.39 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*GP*CP*AP*TP*GP*CP*GP*TP*AP*CP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.37 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 63H 1 x 63H

Experiments and Validation Details

Entry percentile scores
Refinement method: restrained molecular dynamics
Expression system: Not provided

Quick links

Citations

1 review citation

DNA damage by lipid peroxidation products: implications in cancer, inflammation and autoimmunity.
Gentile et al. (2017)
6 other articles

26 mentions without citation

Non-vesicular sterol transport in cells.
Prinz WA. (2007)
25 more