› 2kdg

Solution NMR

Solution Structure of the 1st Ig domain of Myotilin

Released:
DOI: 10.2210/pdb2kdg/pdb
PDB entry 2kdg coloured by chain, ensemble of 25 models, front view.
PDB entry 2kdg coloured by chain, ensemble of 25 models, side view.
PDB entry 2kdg coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the first immunoglobulin domain of human myotilin.
Heikkinen O, Permi P, Koskela H, Carpén O, Ylänne J, Kilpeläinen I
J Biomol NMR 44 107-12 (2009)
PMID: 19418025

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193651 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myotilin Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 10.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UBF9 (Residues: 249-344; Coverage: 19%)
Gene names: MYOT, TTID
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Conserved tryptophan mutation disrupts structure and function of immunoglobulin domain revealing unusual tyrosine fluorescence.
Vattepu et al. (2020)

3 mentions without citation

Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains.
Puž et al. (2017)
2 more