› 2kdo

Solution NMR

Structure of the human Shwachman-Bodian-Diamond syndrome protein, SBDS

Released:
DOI: 10.2210/pdb2kdo/pdb
PDB entry 2kdo coloured by chain, ensemble of 20 models, front view.
PDB entry 2kdo coloured by chain, ensemble of 20 models, side view.
PDB entry 2kdo coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure, dynamics, and RNA interaction analysis of the human SBDS protein.
de Oliveira JF, Sforça ML, Blumenschein TM, Goldfeder MB, Guimarães BG, Oliveira CC, Zanchin NI, Zeri AC
J Mol Biol 396 1053-69 (2010)
PMID: 20053358

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195187 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosome maturation protein SBDS Chain: A
Molecule details ›
Chain: A
Length: 252 amino acids
Theoretical weight: 29.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y3A5 (Residues: 1-250; Coverage: 100%)
Gene names: CGI-97, SBDS
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 74%
Refinement method: DGSA-distance geometry simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Molecular basis of the human ribosomopathy Shwachman-Diamond syndrome.
Warren AJ. (2018)
6 more

3 mentions without citation

Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.
Solania et al. (2019)
2 more