› 2kh9

Solution NMR

Solution structure of yeast Prp24-RRM2 bound to a fragment of U6 RNA

Released:
DOI: 10.2210/pdb2kh9/pdb
PDB entry 2kh9 coloured by chain, ensemble of 10 models, front view.
PDB entry 2kh9 coloured by chain, ensemble of 10 models, side view.
PDB entry 2kh9 coloured by chain, ensemble of 10 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24.
Martin-Tumasz S, Reiter NJ, Brow DA, Butcher SE
RNA 16 792-804 (2010)
PMID: 20181740

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156107 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
U4/U6 snRNA-associated-splicing factor PRP24 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.84 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P49960 (Residues: 115-197; Coverage: 19%)
Gene names: PRP24, YM8156.10C, YMR268C
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
5'-R(*AP*GP*AP*GP*AP*U)-3' Chain: B
Molecule details ›
Chain: B
Length: 6 nucleotides
Theoretical weight: 1.94 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

7 review citations

Structure determination and dynamics of protein-RNA complexes by NMR spectroscopy.
Dominguez et al. (2011)
6 more

3 mentions without citation

Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24.
Martin-Tumasz et al. (2010)
2 more