› 2kha

Solution NMR

Solution Structure of a Pathogen Recognition Domain from a Lepidopteran Insect, Plodia interpunctella

Released:
DOI: 10.2210/pdb2kha/pdb
PDB entry 2kha coloured by chain, ensemble of 20 models, front view.
PDB entry 2kha coloured by chain, ensemble of 20 models, side view.
PDB entry 2kha coloured by chain, ensemble of 20 models, top view.
Source organism: Plodia interpunctella
Primary publication:
An initial event in the insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein.
Dai H, Hiromasa Y, Takahashi D, VanderVelde D, Fabrick JA, Kanost MR, Krishnamoorthi R
Biochemistry 52 161-70 (2013)
PMID: 23237493

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185334 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-1,3-glucan-binding protein Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 14.62 KDa
Source organism: Plodia interpunctella
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8MU95 (Residues: 18-135; Coverage: 25%)
Sequence domains: Carbohydrate binding domain (family 32)
Structure domains: Beta-1,3-glucan-recognition protein, N-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Molecular Interactions of β-(1→3)-Glucans with Their Receptors.
Legentil et al. (2015)
4 more

2 mentions without citation

An initial event in the insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein.
Dai et al. (2013)
1 more