› 2kii

Solution NMR

NMR structure of the SO2144 H-NOX domain from Shewanella oneidensis in the Fe(II)CO ligation state

Released:
DOI: 10.2210/pdb2kii/pdb
PDB entry 2kii coloured by chain, ensemble of 20 models, front view.
PDB entry 2kii coloured by chain, ensemble of 20 models, side view.
PDB entry 2kii coloured by chain, ensemble of 20 models, top view.
Source organism: Shewanella oneidensis
Primary publication:
A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformation.
Erbil WK, Price MS, Wemmer DE, Marletta MA
Proc Natl Acad Sci U S A 106 19753-60 (2009)
PMID: 19918063

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184371 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heme NO-binding domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 181 amino acids
Theoretical weight: 20.53 KDa
Source organism: Shewanella oneidensis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8EF49 (Residues: 1-181; Coverage: 100%)
Gene name: SO_2144
Sequence domains: Haem-NO-binding
Structure domains: H-NOX domain

Ligands and Environments

2 bound ligands:
Ligand HEM 1 x HEM
Ligand CMO 1 x CMO
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Structure and regulation of soluble guanylate cyclase.
Derbyshire et al. (2012)
11 more

5 mentions without citation

A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformation.
Erbil et al. (2009)
4 more