› 2kn8

Solution NMR

NMR structure of the C-terminal domain of pUL89

Released:
DOI: 10.2210/pdb2kn8/pdb
PDB entry 2kn8 coloured by chain, ensemble of 10 models, front view.
PDB entry 2kn8 coloured by chain, ensemble of 10 models, side view.
PDB entry 2kn8 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Insight into the structure of the pUL89 C-terminal domain of the human cytomegalovirus terminase complex.
Couvreux A, Hantz S, Marquant R, Champier G, Alain S, Morellet N, Bouaziz S
Proteins 78 1520-30 (2010)
PMID: 20099308

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180309 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UL89 Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.92 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q6RXE9 (Residues: 568-635; Coverage: 10%)
Gene names: HHV5gp084, UL89
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 46%
Refinement method: distance geometry, simulated annealing
Expression system: Not provided

Quick links

Citations

4 review citations

The human cytomegalovirus terminase complex as an antiviral target: a close-up view.
Ligat et al. (2018)
3 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)