› 2kp2

Solution NMR

Solution structure of the b' domain of thermophilic fungal protein disulfide isomerase

Released:
DOI: 10.2210/pdb2kp2/pdb
PDB entry 2kp2 coloured by chain, ensemble of 10 models, front view.
PDB entry 2kp2 coloured by chain, ensemble of 10 models, side view.
PDB entry 2kp2 coloured by chain, ensemble of 10 models, top view.
Source organism: Humicola insolens
Primary publication:
Redox-dependent domain rearrangement of protein disulfide isomerase coupled with exposure of its substrate-binding hydrophobic surface.
Serve O, Kamiya Y, Maeno A, Nakano M, Murakami C, Sasakawa H, Yamaguchi Y, Harada T, Kurimoto E, Yagi-Utsumi M, Iguchi T, Inaba K, Kikuchi J, Asami O, Kajino T, Oka T, Nakasako M, Kato K
J Mol Biol 396 361-74 (2010)
PMID: 19944705

Function and Biology Details

Reaction catalysed: 
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157167 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein disulfide-isomerase Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.51 KDa
Source organism: Humicola insolens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55059 (Residues: 228-355; Coverage: 26%)
Sequence domains: Thioredoxin-like domain
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

10 review citations

A structural overview of the PDI family of proteins.
Kozlov et al. (2010)
9 more