› 2kpl

Solution NMR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136591 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 13.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96QZ7 (Residues: 455-580; Coverage: 9%)
Gene names: AIP3, BAIAP1, BAP1, MAGI1, TNRC19
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Protein E6 Chain: B
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.38 KDa
Source organism: Human papillomavirus 16
Expression system: Escherichia coli
UniProt:
  • Canonical: P03126 (Residues: 148-157; Coverage: 6%)
Gene name: E6

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Papillomavirus E6 oncoproteins.
Vande Pol et al. (2013)
10 more

12 mentions without citation

In Silico Approaches: A Way to Unveil Novel Therapeutic Drugs for Cervical Cancer Management.
Gomes et al. (2021)
11 more