› 2kpv

Solution NMR

NMR model of the first let-7 miRNA complementary site (LCS1) in 3'-UTR of lin-41 mRNA from C. elegans

Released:
DOI: 10.2210/pdb2kpv/pdb
PDB entry 2kpv coloured by chain, ensemble of 10 models, front view.
PDB entry 2kpv coloured by chain, ensemble of 10 models, side view.
PDB entry 2kpv coloured by chain, ensemble of 10 models, top view.
Source organism: Synthetic construct
Primary publication:
NMR structure of the let-7 miRNA interacting with the site LCS1 of lin-41 mRNA from Caenorhabditis elegans.
Cevec M, Thibaudeau C, Plavec J
Nucleic Acids Res 38 7814-21 (2010)
PMID: 20660479

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196426 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (34-MER) Chain: A
Molecule details ›
Chain: A
Length: 34 nucleotides
Theoretical weight: 10.95 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, energy minimization
Expression system: Not provided

Quick links

Citations

4 review citations

The emerging role of microRNAs in the pathogenesis of systemic lupus erythematosus.
Miao et al. (2013)
3 more

4 mentions without citation

Predicting 3D Structure, Flexibility, and Stability of RNA Hairpins in Monovalent and Divalent Ion Solutions.
Shi et al. (2015)
3 more