› 2kpw

Solution NMR

NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium MEGA target, HR5546A (439-549)

Released:
DOI: 10.2210/pdb2kpw/pdb
PDB entry 2kpw coloured by chain, ensemble of 20 models, front view.
PDB entry 2kpw coloured by chain, ensemble of 20 models, side view.
PDB entry 2kpw coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Swapna GVT, Ciccosanti CL, Belote R, Hamilton K, Acton T, Huang Y, Xiao R, Everett J, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149029 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lamin-B1 Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 13.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P20700 (Residues: 439-549; Coverage: 19%)
Gene names: LMN2, LMNB, LMNB1
Sequence domains: Lamin Tail Domain
Structure domains: Lamin Tail domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 87%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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