› 2ks4

Solution NMR

NMR structure of the sea anemone actinoporin Sticholysin

Released:
DOI: 10.2210/pdb2ks4/pdb
PDB entry 2ks4 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ks4 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ks4 coloured by chain, ensemble of 20 models, top view.
Source organism: Stichodactyla helianthus
Primary publication:
1H, 13C, and 15N NMR assignments of the actinoporin Sticholysin I.
Castrillo I, Alegre-Cebollada J, del Pozo AM, Gavilanes JG, Santoro J, Bruix M
Biomol NMR Assign 3 5-7 (2009)
PMID: 19636934

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DELTA-stichotoxin-She4a Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 19.41 KDa
Source organism: Stichodactyla helianthus
Expression system: Escherichia coli
UniProt:
  • Canonical: P81662 (Residues: 1-176; Coverage: 100%)
Sequence domains: Sea anemone cytotoxic protein
Structure domains: Cytolysin/lectin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli

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Citations

2 review citations

The multigene families of actinoporins (part I): Isoforms and genetic structure.
Valle et al. (2015)
1 more

9 mentions without citation

Sea Anemone Toxins: A Structural Overview.
Madio et al. (2019)
8 more