› 2kv0

Solution NMR

2-Aminopurine incorporation perturbs the dynamics and structure of DNA

Released:
DOI: 10.2210/pdb2kv0/pdb
PDB entry 2kv0 coloured by chain, ensemble of 11 models, front view.
PDB entry 2kv0 coloured by chain, ensemble of 11 models, side view.
PDB entry 2kv0 coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
2-Aminopurine incorporation perturbs the dynamics and structure of DNA.
Dallmann A, Dehmel L, Peters T, Mügge C, Griesinger C, Tuma J, Ernsting NP
Angew Chem Int Ed Engl 49 5989-92 (2010)
PMID: 20632340

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115504 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*GP*CP*TP*GP*CP*AP*(2PR)P*AP*CP*GP*TP*CP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 13 nucleotides
Theoretical weight: 3.98 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*CP*GP*AP*CP*GP*TP*TP*TP*GP*CP*AP*GP*C)-3') Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 3.97 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 2PR 1 x 2PR

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

3 review citations

2-Aminopurine as a fluorescent probe of DNA conformation and the DNA-enzyme interface.
Jones et al. (2015)
2 more

2 mentions without citation

Bridging the resolution gap in structural modeling of 3D genome organization.
Marti-Renom et al. (2011)
1 more